A Sr Research Associate to develop novel library construction methods/NGS assays that address difficult questions related to CF disease biology/pathology. She/He will work as part of a team in the operation of the Next Generation Sequencing (NGS) and Genomics laboratory to achieve departmental goals. Responsibilities include hands on preparation of NGS libraries, operation and maintenance of NGS instrumentation including Single Cell, Next Generation, and Third Generation sequencing platforms. Strong ability to troubleshoot routine as well as novel NGS assays such as target enrichment methods, Chip-Seq, ATAC-seq, and other methods to explore chromatin biology.
Areas of Responsibility:
- Nucleic acid extraction and QC.
- Manipulation of DNA (PCR, Electrophoresis, etc.).
- NGS library preparation.
- Operation and maintenance of NGS instrumentation.
- Troubleshooting and Quality Control of library construction and sequencing runs.
- Participate in group meetings for discussion of data and suggested next steps.
- Maintain detailed records of the work carried out (electronic lab notebook).
- Prepare and present results at internal meetings.
- Participate in annual Great Strides Walk and related events organized by the Foundation to help people with CF.
Educational Background:
B.S./M.S. in Life Sciences with 4+ years R+D lab experience.
Skills/Experience:
- Familiarity with analytic tools and methods for NGS data analysis.
- Excellent attention to detail.
- Experience with Single Cell RNA-seq, Chip-Seq, ATAC-seq, Long Read Sequencing.
- Experience troubleshooting various NGS assays.
- Excellent communication, collaboration, problem solving skills.
- Detail-oriented and capable of multi-tasking in a dynamic team.
REPORTING RELATIONSHIPS:
- Head of NGS and Genomics.
WORKING CONDITIONS:
- Commute to lab every workday.
- Research Lab with chemical and biological hazards present.
- Must have access to reliable transportation.
- Use of computer required.
- Must be able to work from home when road conditions do not permit travel to workplace.
- Sitting, bending, reaching, and walking.
Job Function:
Organization Info
Listing Stats
Post Date:
Jan 21 2019
Active Until:
Feb 21 2019
Hiring Organization:
Cystic Fibrosis Foundation
industry:
Nonprofit