Senior/Principal Scientist – Bioinformatics

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Cystic Fibrosis Foundation
Lexington, MA, United States
Full-time

The Cystic Fibrosis Foundation, a highly regarded non-profit organization focused on curing CF, is seeking a Head of Bioinformatics.  The position will be at the Foundation’s growing R&D laboratory in Lexington, MA.

Areas of Responsibility: 
  • The successful candidate will have a PhD in a relevant field and 4+ years experience in designing, running, and overseeing various DNA and RNA NGS assays. 
  • The Head of Bioinformatics will oversee several independent, but related, activities at the Lexington laboratory, and is expected to build a small productive team.  The work will include DNA sequencing and resulting data analysis as required for ongoing projects in gene-editing and stem cell model development, single-cell RNA SEQ, ribosome profiling experiments, as well as occasional whole genome sequencing. 
  • The bioinformatics team is also expected to help with other bioinformatics needs of the lab, e.g. automation of data analysis from various in house assays.  In addition, the head of bioinformatics may also interface with the VP of BioPharma Programs and leading academics as part of a larger effort to utilize emerging WGS data in combination with rich attendant longitudinal clinical data.
  • The candidate is expected to present work and progress at internal meetings and select conferences.
Educational Background: 
Doctorate degree with 4+ years of relevant experience in relevant data analyses in academia or biotech/pharma.
Skills/Experience: 
  • Prior experience in designing and execution of sequencing assays, e.g.
    • whole gene sequencing and phasing
    • identification of off-target events in gene editing
    • RNA seq and single cell RNA seq
    • ribosome profiling a
    • whole genome sequencing
  • Prior experience with large (confidential) sequencing datasets is desired.
  • Ability to work as part of a collaborative group.
  • High standards of excellence and track record of productivity.
  • Experience in managing a small team desired.
  • Detail-oriented and capable of multi-tasking in a dynamic team.
  • Demonstrated productivity in developing new and unique analytic approaches, preferably involving large data sets is a plus.
How to Apply: 

https://chk.tbe.taleo.net/chk01/ats/careers/requisition.jsp?org=CFF&cws=...

Job Function: 
Program / Project Management

Organization Info

Cystic Fibrosis Foundation

Overview
Headquarters: 
Bethesda, MD, United States
Website: 
cff.org
Founded: 
1957
About Us
Areas of Focus: 
Diseases / Disorders
Medical Research
Mission: 

The mission of the Cystic Fibrosis Foundation is to cure cystic fibrosis and to provide all people with the disease the opportunity to lead full, productive lives by funding research and drug development, promoting individualized treatment and ensuring access to high-quality, specialized care.

The Cystic Fibrosis Foundation has 70 chapters and branch offices across the country that work diligently to raise funds to help support the search for a cure. In addition, the Foundation provides funding for and accredits more than 120 CF care centers and 53 affiliate programs nationwide, including more than 100 programs for treating adults with CF. The high quality of specialized care available throughout the care center network has led to the improved length and quality of life for people with CF. Located at teaching and community hospitals across the country, these care centers offer the best care, treatments and support for those with CF.

Listing Stats

Post Date: 
Sep 15 2017
Active Until: 
Oct 15 2017
Hiring Organization: 
Cystic Fibrosis Foundation
industry: 
Nonprofit